Bonavita, Roberta (2015) Bacillus subtilis as Mucosal Adjuvant. [Tesi di dottorato]

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Item Type: Tesi di dottorato
Resource language: English
Title: Bacillus subtilis as Mucosal Adjuvant
Creators:
CreatorsEmail
Bonavita, Robertarob.bonavita@live.it
Date: 29 March 2015
Number of Pages: 95
Institution: Università degli Studi di Napoli Federico II
Department: Biologia
Scuola di dottorato: Scienze biologiche
Dottorato: Biologia applicata
Ciclo di dottorato: 27
Coordinatore del Corso di dottorato:
nomeemail
Ricca, Ezioericca@unina.it
Tutor:
nomeemail
Ricca, EzioUNSPECIFIED
Date: 29 March 2015
Number of Pages: 95
Keywords: Bacillus subtilis spores, gliadin, immunomodulatory strategies
Settori scientifico-disciplinari del MIUR: Area 05 - Scienze biologiche > BIO/13 - Biologia applicata
Area 05 - Scienze biologiche > BIO/19 - Microbiologia generale
Aree tematiche (7° programma Quadro): BIOTECNOLOGIE, PRODOTTI ALIMENTARI E AGRICOLTURA > "Fork to farm" - Prodotti alimentari (inclusi prodotti ittici), salute e benessere
BIOTECNOLOGIE, PRODOTTI ALIMENTARI E AGRICOLTURA > Scienze della vita, biotecnologia e biochimica per prodotti e processi non-alimentari sostenibili
Date Deposited: 07 Apr 2015 08:18
Last Modified: 14 Nov 2015 02:00
URI: http://www.fedoa.unina.it/id/eprint/10158
DOI: 10.6092/UNINA/FEDOA/10158

Collection description

Recently, researches attention has been focused on the development of mucosal immunity strategies based on the use of probiotic spores as mucosal adjuvant. Therefore, they represent a good adjuvant to deliver antigens into the gastrointestinal tract and they could be used to mucosal vaccine. The mucosal vaccinology was used also for down-regulating inflammatory conditions. Among these conditions, celiac disease (CD) represents a very interesting model to test possible immunomodulatory strategies. So the aim of my research has been the use of Bacillus subtilis spores as a display system to development an immunomodulatory strategies for celiac disease.

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