Bonavita, Roberta (2015) Bacillus subtilis as Mucosal Adjuvant. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato | ||||
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| Lingua: | English | ||||
| Title: | Bacillus subtilis as Mucosal Adjuvant | ||||
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| Date: | 29 March 2015 | ||||
| Number of Pages: | 95 | ||||
| Institution: | Università degli Studi di Napoli Federico II | ||||
| Department: | Biologia | ||||
| Scuola di dottorato: | Scienze biologiche | ||||
| Dottorato: | Biologia applicata | ||||
| Ciclo di dottorato: | 27 | ||||
| Coordinatore del Corso di dottorato: |
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| Tutor: |
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| Date: | 29 March 2015 | ||||
| Number of Pages: | 95 | ||||
| Uncontrolled Keywords: | Bacillus subtilis spores, gliadin, immunomodulatory strategies | ||||
| Settori scientifico-disciplinari del MIUR: | Area 05 - Scienze biologiche > BIO/13 - Biologia applicata Area 05 - Scienze biologiche > BIO/19 - Microbiologia generale |
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| Aree tematiche (7° programma Quadro): | BIOTECNOLOGIE, PRODOTTI ALIMENTARI E AGRICOLTURA > "Fork to farm" - Prodotti alimentari (inclusi prodotti ittici), salute e benessere BIOTECNOLOGIE, PRODOTTI ALIMENTARI E AGRICOLTURA > Scienze della vita, biotecnologia e biochimica per prodotti e processi non-alimentari sostenibili |
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| Date Deposited: | 07 Apr 2015 08:18 | ||||
| Last Modified: | 14 Nov 2015 02:00 | ||||
| URI: | http://www.fedoa.unina.it/id/eprint/10158 | ||||
| DOI: | 10.6092/UNINA/FEDOA/10158 |
Abstract
Recently, researches attention has been focused on the development of mucosal immunity strategies based on the use of probiotic spores as mucosal adjuvant. Therefore, they represent a good adjuvant to deliver antigens into the gastrointestinal tract and they could be used to mucosal vaccine. The mucosal vaccinology was used also for down-regulating inflammatory conditions. Among these conditions, celiac disease (CD) represents a very interesting model to test possible immunomodulatory strategies. So the aim of my research has been the use of Bacillus subtilis spores as a display system to development an immunomodulatory strategies for celiac disease.
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