Marzaioli, Alberto Maria
(2015)
Structure/activity evaluation of the bacterial membrane constituents involved in the immune system.
[Tesi di dottorato]
| Tipologia del documento: |
Tesi di dottorato
|
| Lingua: |
English |
| Titolo: |
Structure/activity evaluation of the bacterial membrane constituents involved in the immune system |
| Autori: |
| Autore | Email |
|---|
| Marzaioli, Alberto Maria | albertomaria.marzaioli@unina.it |
|
| Data: |
31 Marzo 2015 |
| Numero di pagine: |
147 |
| Istituzione: |
Università degli Studi di Napoli Federico II |
| Dipartimento: |
Scienze Chimiche |
| Scuola di dottorato: |
Scienze chimiche |
| Dottorato: |
Scienze chimiche |
| Ciclo di dottorato: |
27 |
| Coordinatore del Corso di dottorato: |
| nome | email |
|---|
| Paduano, Luigi | luigi.paduano@unina.it |
|
| Tutor: |
| nome | email |
|---|
| De Castro, Cristina | [non definito] |
|
| Data: |
31 Marzo 2015 |
| Numero di pagine: |
147 |
| Parole chiave: |
CARBOHYDRATES, ORGANIC CHEMISTRY, NMR, GC-MS, MALDI |
| Settori scientifico-disciplinari del MIUR: |
Area 03 - Scienze chimiche > CHIM/06 - Chimica organica |
[error in script]
[error in script]
| Depositato il: |
09 Apr 2015 09:15 |
| Ultima modifica: |
07 Ott 2015 08:29 |
| URI: |
http://www.fedoa.unina.it/id/eprint/10391 |
| DOI: |
10.6092/UNINA/FEDOA/10391 |
Abstract
The Lipopolysaccharides (LPSs) are the major constituents of the outer membrane of Gram-negative bacteria and with capsular polysaccharides (CPSs) and peptidoglycan (PGN) are involved in the interaction with immune system receptors.
The chemical characterization of these molecules is fundamental for the elucidation of correlation existing between the structure and the biological activity.
The present thesis deals with the structural study of Lipopolysaccharides and Capsular polysaccharides from different Gram-negative bacteria.
The last part of thesis is focused on the preparation of the building block for the synthesis of new glycoconjugates with potential activity against HIV-1.
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