Marzaioli, Alberto Maria (2015) Structure/activity evaluation of the bacterial membrane constituents involved in the immune system. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato |
|---|---|
| Resource language: | English |
| Title: | Structure/activity evaluation of the bacterial membrane constituents involved in the immune system |
| Creators: | Creators Email Marzaioli, Alberto Maria albertomaria.marzaioli@unina.it |
| Date: | 31 March 2015 |
| Number of Pages: | 147 |
| Institution: | Università degli Studi di Napoli Federico II |
| Department: | Scienze Chimiche |
| Scuola di dottorato: | Scienze chimiche |
| Dottorato: | Scienze chimiche |
| Ciclo di dottorato: | 27 |
| Coordinatore del Corso di dottorato: | nome email Paduano, Luigi luigi.paduano@unina.it |
| Tutor: | nome email De Castro, Cristina UNSPECIFIED |
| Date: | 31 March 2015 |
| Number of Pages: | 147 |
| Keywords: | CARBOHYDRATES, ORGANIC CHEMISTRY, NMR, GC-MS, MALDI |
| Settori scientifico-disciplinari del MIUR: | Area 03 - Scienze chimiche > CHIM/06 - Chimica organica |
| Date Deposited: | 09 Apr 2015 09:15 |
| Last Modified: | 07 Oct 2015 08:29 |
| URI: | http://www.fedoa.unina.it/id/eprint/10391 |
| DOI: | 10.6092/UNINA/FEDOA/10391 |
Collection description
The Lipopolysaccharides (LPSs) are the major constituents of the outer membrane of Gram-negative bacteria and with capsular polysaccharides (CPSs) and peptidoglycan (PGN) are involved in the interaction with immune system receptors. The chemical characterization of these molecules is fundamental for the elucidation of correlation existing between the structure and the biological activity. The present thesis deals with the structural study of Lipopolysaccharides and Capsular polysaccharides from different Gram-negative bacteria. The last part of thesis is focused on the preparation of the building block for the synthesis of new glycoconjugates with potential activity against HIV-1.
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