Trinchillo, Marina (2016) NOVEL AU(I)-BASED MOLECULAR CATALYSTS: FROM KNOW HOW TO KNOW WHY. [Tesi di dottorato]

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Item Type: Tesi di dottorato
Lingua: English
Title: NOVEL AU(I)-BASED MOLECULAR CATALYSTS: FROM KNOW HOW TO KNOW WHY
Creators:
CreatorsEmail
Trinchillo, MarinaMARINA.TRINCHILLO@UNINA.IT
Date: 31 March 2016
Number of Pages: 254
Institution: Università degli Studi di Napoli Federico II
Department: Scienze Chimiche
Scuola di dottorato: Scienze chimiche
Dottorato: Scienze chimiche
Ciclo di dottorato: 28
Coordinatore del Corso di dottorato:
nomeemail
Paduano, LuigiLPADUANO@UNINA.IT
Tutor:
nomeemail
Busico, VincenzoUNSPECIFIED
D'Amora, AngelaUNSPECIFIED
Date: 31 March 2016
Number of Pages: 254
Uncontrolled Keywords: GOLD CATALYSIS - HOMOGENEOUS CATALYSIS - ALKOXYLATION - ANION EFFECT - NHC COMPOUNDS - FUNCTIONALIZED NHC LIGANDS - ANTIPROLIFERATIVE ACTIVITY
Settori scientifico-disciplinari del MIUR: Area 03 - Scienze chimiche > CHIM/03 - Chimica generale e inorganica
Date Deposited: 11 Apr 2016 17:03
Last Modified: 20 May 2017 01:00
URI: http://www.fedoa.unina.it/id/eprint/11000

Abstract

In recent years, linear gold(I) complexes have been vastly employed in both homogeneous catalysis and medicinal applications, as anticancer agents. In this thesis novel Au(I)-complexes have been synthesized and their catalytic behavior has been deeply studied in the hydroalkoxylation reaction of alkynes, with particular focus on the role of the anion in different steps of the catalytic cycle, obtaining very interesting results. Furthermore, gold(I) compounds were screened for their antiproliferative effects on different cell lines, and in some cases very promising cytotoxic properties were found.

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