Saggese, Anella
(2017)
Analysis of the spore structure in the model species Bacillus subtilis and Bacillus megaterium.
[Tesi di dottorato]
Item Type: |
Tesi di dottorato
|
Lingua: |
English |
Title: |
Analysis of the spore structure in the model species Bacillus subtilis and Bacillus megaterium |
Creators: |
Creators | Email |
---|
Saggese, Anella | ornellasaggese2010@libero.it |
|
Date: |
7 April 2017 |
Number of Pages: |
108 |
Institution: |
Università degli Studi di Napoli Federico II |
Department: |
Biologia |
Dottorato: |
Biologia |
Ciclo di dottorato: |
29 |
Coordinatore del Corso di dottorato: |
nome | email |
---|
Cozzolino, Salvatore | salvatore.cozzolino@unina.it |
|
Tutor: |
nome | email |
---|
Baccigalupi, Loredana | UNSPECIFIED |
|
Date: |
7 April 2017 |
Number of Pages: |
108 |
Uncontrolled Keywords: |
Bacillus subtilis, Bacillus megaterium, spores |
Settori scientifico-disciplinari del MIUR: |
Area 05 - Scienze biologiche > BIO/19 - Microbiologia generale |
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Date Deposited: |
20 Apr 2017 11:34 |
Last Modified: |
16 Mar 2018 13:09 |
URI: |
http://www.fedoa.unina.it/id/eprint/11502 |
DOI: |
10.6093/UNINA/FEDOA/11502 |

Abstract
In my PhD project I studied two bacteria of the same genus, Bacillus subtilis and Bacillus megaterium. These organisms are Gram-positive, spore formers and, therefore, share the ability to undergo a complex developmental cell differentiation process and produce highly resistant spores. My studies focused on the molecular characterization of the spore surface of these two bacterial species. In particular I characterized the role of three coat components, CotG, CotH and CotE in Bacillus subtilis and I identified a protein involved in the exosporium assembly in Bacillus megaterium. I also investigated on the possibility to use B. megaterium spores as a platform to display heterologous proteins with various biological activities on their surface in order to use them for biotechnological applications.
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