Saggese, Anella (2017) Analysis of the spore structure in the model species Bacillus subtilis and Bacillus megaterium. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato |
|---|---|
| Resource language: | English |
| Title: | Analysis of the spore structure in the model species Bacillus subtilis and Bacillus megaterium |
| Creators: | Creators Email Saggese, Anella ornellasaggese2010@libero.it |
| Date: | 7 April 2017 |
| Number of Pages: | 108 |
| Institution: | Università degli Studi di Napoli Federico II |
| Department: | Biologia |
| Dottorato: | Biologia |
| Ciclo di dottorato: | 29 |
| Coordinatore del Corso di dottorato: | nome email Cozzolino, Salvatore salvatore.cozzolino@unina.it |
| Tutor: | nome email Baccigalupi, Loredana UNSPECIFIED |
| Date: | 7 April 2017 |
| Number of Pages: | 108 |
| Keywords: | Bacillus subtilis, Bacillus megaterium, spores |
| Settori scientifico-disciplinari del MIUR: | Area 05 - Scienze biologiche > BIO/19 - Microbiologia generale |
| Date Deposited: | 20 Apr 2017 11:34 |
| Last Modified: | 16 Mar 2018 13:09 |
| URI: | http://www.fedoa.unina.it/id/eprint/11502 |
| DOI: | 10.6093/UNINA/FEDOA/11502 |
Collection description
In my PhD project I studied two bacteria of the same genus, Bacillus subtilis and Bacillus megaterium. These organisms are Gram-positive, spore formers and, therefore, share the ability to undergo a complex developmental cell differentiation process and produce highly resistant spores. My studies focused on the molecular characterization of the spore surface of these two bacterial species. In particular I characterized the role of three coat components, CotG, CotH and CotE in Bacillus subtilis and I identified a protein involved in the exosporium assembly in Bacillus megaterium. I also investigated on the possibility to use B. megaterium spores as a platform to display heterologous proteins with various biological activities on their surface in order to use them for biotechnological applications.
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