Scarpato, Elena (2017) Insights on Functional Gastrointestinal Disorders in Children: Pathogenesis, Prevalence, and Clinical Management. [Tesi di dottorato]
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Tipologia del documento: | Tesi di dottorato |
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Lingua: | English |
Titolo: | Insights on Functional Gastrointestinal Disorders in Children: Pathogenesis, Prevalence, and Clinical Management |
Autori: | Autore Email Scarpato, Elena elenascarpato@hotmail.it |
Data: | 6 Dicembre 2017 |
Numero di pagine: | 99 |
Istituzione: | Università degli Studi di Napoli Federico II |
Dipartimento: | dep22 |
Dottorato: | phd053 |
Ciclo di dottorato: | 30 |
Coordinatore del Corso di dottorato: | nome email Marone, Gianni gianni.marone@unina.it |
Tutor: | nome email Staiano, Annamaria [non definito] |
Data: | 6 Dicembre 2017 |
Numero di pagine: | 99 |
Parole chiave: | functional gastrointestinal disorders, epidemiology, pathogenetic hypothesis |
Settori scientifico-disciplinari del MIUR: | Area 06 - Scienze mediche > MED/12 - Gastroenterologia Area 06 - Scienze mediche > MED/38 - Pediatria generale e specialistica |
Depositato il: | 21 Dic 2017 09:13 |
Ultima modifica: | 11 Apr 2019 10:37 |
URI: | http://www.fedoa.unina.it/id/eprint/12049 |
Abstract
Functional gastrointestinal disorders (FGIDs) include a combination of chronic or recurrent gastrointestinal symptoms not explained by biochemical or structural abnormalities. The precise pathogenetic mechanism leading to the onset of FGIDs is unclear. FGIDs are currently diagnosed according to the Rome criteria, that allow a "positive" diagnosis, without performing invasive tests. However, in spite of the Rome criteria, diagnostic approach to FGIDs still varies widely among different countries due to several factors, including cultural customs. Over the last years, interest in the study and recognition of FGIDs in children has increased. Nevertheless, despite some promising developments, more research is needed to further understand the pathophysiology and treatment of these conditions that remain one of the great challenges in modern paediatric gastroenterological practice. The main aims of the present Ph.D. thesis were: 1. to evaluate the current diagnostic-therapeutic approach to FGIDs; 2. to define the prevalence of FGIDs in the Mediterranean part of Europe; 3. to improve and standardize clinical trials in FGIDs.
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