Scarpato, Elena (2017) Insights on Functional Gastrointestinal Disorders in Children: Pathogenesis, Prevalence, and Clinical Management. [Tesi di dottorato]

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Item Type: Tesi di dottorato
Lingua: English
Title: Insights on Functional Gastrointestinal Disorders in Children: Pathogenesis, Prevalence, and Clinical Management
Creators:
CreatorsEmail
Scarpato, Elenaelenascarpato@hotmail.it
Date: 6 December 2017
Number of Pages: 99
Institution: Università degli Studi di Napoli Federico II
Department: dep22
Dottorato: phd053
Ciclo di dottorato: 30
Coordinatore del Corso di dottorato:
nomeemail
Marone, Giannigianni.marone@unina.it
Tutor:
nomeemail
Staiano, AnnamariaUNSPECIFIED
Date: 6 December 2017
Number of Pages: 99
Uncontrolled Keywords: functional gastrointestinal disorders, epidemiology, pathogenetic hypothesis
Settori scientifico-disciplinari del MIUR: Area 06 - Scienze mediche > MED/12 - Gastroenterologia
Area 06 - Scienze mediche > MED/38 - Pediatria generale e specialistica
Date Deposited: 21 Dec 2017 09:13
Last Modified: 11 Apr 2019 10:37
URI: http://www.fedoa.unina.it/id/eprint/12049

Abstract

Functional gastrointestinal disorders (FGIDs) include a combination of chronic or recurrent gastrointestinal symptoms not explained by biochemical or structural abnormalities. The precise pathogenetic mechanism leading to the onset of FGIDs is unclear. FGIDs are currently diagnosed according to the Rome criteria, that allow a "positive" diagnosis, without performing invasive tests. However, in spite of the Rome criteria, diagnostic approach to FGIDs still varies widely among different countries due to several factors, including cultural customs. Over the last years, interest in the study and recognition of FGIDs in children has increased. Nevertheless, despite some promising developments, more research is needed to further understand the pathophysiology and treatment of these conditions that remain one of the great challenges in modern paediatric gastroenterological practice. The main aims of the present Ph.D. thesis were: 1. to evaluate the current diagnostic-therapeutic approach to FGIDs; 2. to define the prevalence of FGIDs in the Mediterranean part of Europe; 3. to improve and standardize clinical trials in FGIDs.

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