Aiello, Eugenio
(2017)
THE SAFETY ASSESSMENT OF HERBALS WITH A NEW AND
ETHICAL APPROACH.
[Tesi di dottorato]
| Item Type: |
Tesi di dottorato
|
| Resource language: |
English |
| Title: |
THE SAFETY ASSESSMENT OF HERBALS WITH A NEW AND
ETHICAL APPROACH |
| Creators: |
| Creators | Email |
|---|
| Aiello, Eugenio | aielloeugenio@gmail.com |
|
| Date: |
10 December 2017 |
| Number of Pages: |
101 |
| Institution: |
Università degli Studi di Napoli Federico II |
| Department: |
dep05 |
| Dottorato: |
phd071 |
| Ciclo di dottorato: |
30 |
| Coordinatore del Corso di dottorato: |
| nome | email |
|---|
| D'Auria, Maria Valeria | madauria@unina.it |
|
| Tutor: |
| nome | email |
|---|
| Calignano, Antonio | UNSPECIFIED |
|
| Date: |
10 December 2017 |
| Number of Pages: |
101 |
| Keywords: |
NOEL - REGULATORY - TOXICOLOGY - SAFETY ASSESSMENT |
| Settori scientifico-disciplinari del MIUR: |
Area 05 - Scienze biologiche > BIO/01 - Botanica generale
Area 05 - Scienze biologiche > BIO/14 - Farmacologia |
[error in script]
[error in script]
| Date Deposited: |
19 Dec 2017 12:59 |
| Last Modified: |
22 Mar 2019 10:49 |
| URI: |
http://www.fedoa.unina.it/id/eprint/12161 |
Collection description
The increasing use of plant medicines (herbals) in Europe needs a shared methodology to determine the toxicity and the daily exposure level to these drugs. For this reason, the European regulatory agencies have undertaken a study that could meet popular uses and toxicological research in di erent countries of the Union. Here we list some examples of the most used herbal drug classes and we propose a decision-making process based on their characteristics, their content in active principles and on the basis of the present scientific pharmacological and toxicological literature. The proposed decision tree actually makes easier for the assessor to quickly and accurately evaluate the accredited indexes for risk and toxicity assessment based on the preclinical literature data and using the correct classi cation that some of them may have because they are already present in medicinal products or used as food.
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