ALCIDI, BRUNELLA (2018) Identification and characterization of anti-caries natural compounds and their use in experimental slow release tablets as advancement of oral health strategies. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato |
|---|---|
| Resource language: | English |
| Title: | Identification and characterization of anti-caries natural compounds and their use in experimental slow release tablets as advancement of oral health strategies. |
| Creators: | Creators Email ALCIDI, BRUNELLA brunella.alcidi@gmail.com |
| Date: | June 2018 |
| Number of Pages: | 57 |
| Institution: | Università degli Studi di Napoli Federico II |
| Department: | dep16 |
| Dottorato: | phd053 |
| Ciclo di dottorato: | 30 |
| Coordinatore del Corso di dottorato: | nome email Marone, Gianni marone@unina.iT |
| Tutor: | nome email Ingenito, Aniello UNSPECIFIED |
| Date: | June 2018 |
| Number of Pages: | 57 |
| Keywords: | CARIES, NATURAL COMPOUNDS, MUCADHESIVE TABLETS. |
| Settori scientifico-disciplinari del MIUR: | Area 06 - Scienze mediche > MED/28 - Malattie odontostomatologiche |
| Date Deposited: | 22 Jun 2018 06:41 |
| Last Modified: | 12 Mar 2019 10:57 |
| URI: | http://www.fedoa.unina.it/id/eprint/12289 |
Collection description
The intent of this research program was to determine a new way in caries prevention. The score was the development of new formulation for topical administration of natural anti-caries active compounds in the oral cavity. Mucoadhesive tablets containing CPP-ACP, Stevia rebaudiana Bertoni and pomegranate peel extract, after excluding any citotossic activity, were performed .The tablets have been evaluated in terms of swelling, mucoadhesion and organoleptic characteristics. On the basis of the results obtained from this research, the usage of mucoadhesive buccal drug delivery system could be a novel route of anticaries bio-active molecules administration by offering prolonged contact at the site of administration and satisfying the compliance of the patients.
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