ALCIDI, BRUNELLA
(2018)
Identification and characterization of anti-caries natural compounds and their use in experimental slow release tablets as advancement of oral health strategies.
[Tesi di dottorato]
| Tipologia del documento: |
Tesi di dottorato
|
| Lingua: |
English |
| Titolo: |
Identification and characterization of anti-caries natural compounds and their use in experimental slow release tablets as advancement of oral health strategies. |
| Autori: |
| Autore | Email |
|---|
| ALCIDI, BRUNELLA | brunella.alcidi@gmail.com |
|
| Data: |
Giugno 2018 |
| Numero di pagine: |
57 |
| Istituzione: |
Università degli Studi di Napoli Federico II |
| Dipartimento: |
dep16 |
| Dottorato: |
phd053 |
| Ciclo di dottorato: |
30 |
| Coordinatore del Corso di dottorato: |
| nome | email |
|---|
| Marone, Gianni | marone@unina.iT |
|
| Tutor: |
| nome | email |
|---|
| Ingenito, Aniello | [non definito] |
|
| Data: |
Giugno 2018 |
| Numero di pagine: |
57 |
| Parole chiave: |
CARIES, NATURAL COMPOUNDS, MUCADHESIVE TABLETS. |
| Settori scientifico-disciplinari del MIUR: |
Area 06 - Scienze mediche > MED/28 - Malattie odontostomatologiche |
[error in script]
[error in script]
| Depositato il: |
22 Giu 2018 06:41 |
| Ultima modifica: |
12 Mar 2019 10:57 |
| URI: |
http://www.fedoa.unina.it/id/eprint/12289 |
Abstract
The intent of this research program was to determine a new way in caries prevention. The score was the development of new formulation for topical administration of natural anti-caries active compounds in the oral cavity. Mucoadhesive tablets containing CPP-ACP, Stevia rebaudiana Bertoni and pomegranate peel extract, after excluding any citotossic activity, were performed .The tablets have been evaluated in terms of swelling, mucoadhesion and organoleptic characteristics. On the basis of the results obtained from this research, the usage of mucoadhesive buccal drug delivery system could be a novel route of anticaries bio-active molecules administration by offering prolonged contact at the site of administration and satisfying the compliance of the patients.
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