Cruz Maya, Iriczalli (2020) Preparation and Characterization of Scaffolds for Tissue Engineering. [Tesi di dottorato]


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Item Type: Tesi di dottorato
Lingua: English
Title: Preparation and Characterization of Scaffolds for Tissue Engineering
Cruz Maya,
Date: 10 March 2020
Number of Pages: 153
Institution: Università degli Studi di Napoli Federico II
Department: Ingegneria Chimica, dei Materiali e della Produzione Industriale
Dottorato: Ingegneria dei prodotti e dei processi industriali
Ciclo di dottorato: 32
Coordinatore del Corso di dottorato:
Mensitieri, GiuseppeUNSPECIFIED
Guarino, VincenzoUNSPECIFIED
Date: 10 March 2020
Number of Pages: 153
Uncontrolled Keywords: Electrofluidodynmics; Proteins; Fibers; In vitro studies
Settori scientifico-disciplinari del MIUR: Area 03 - Scienze chimiche > CHIM/05 - Scienza e tecnologia dei materiali polimerici
Area 09 - Ingegneria industriale e dell'informazione > ING-IND/22 - Scienza e tecnologia dei materiali
Date Deposited: 22 Mar 2020 23:05
Last Modified: 10 Nov 2021 11:33


The main challenge of tissue engineering is to design scaffolds able to reproduce the natural environment of cells, it means, the native extracellular matrix by including morphological and biochemical cues. From the morphological point of view, natural ECM may be organized randomly or aligned or semi-aligned, meanwhile, the addition of natural polymers is able to improve the biological properties of biomaterials. In this work, it will be explored the use of electrofluidodynamic technologies (EFDTs), namely electrospinning and electrospraying for the development of bioinspired devices for the application in tissue engineering and drug delivery systems. Different strategies were developed via EFDTs by using different biomaterials such as natural proteins and created oriented fibers to improve the cell-material interaction through chemical and morphological signals.


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