Gargano, Barbara (2008) Positive and negative regulation of Myc-mediated transcription. [Tesi di dottorato] (Unpublished)

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Item Type: Tesi di dottorato
Language: English
Title: Positive and negative regulation of Myc-mediated transcription
Creators:
CreatorsEmail
Gargano, Barbarabarbara.gargano@unina.it
Date: 3 December 2008
Number of Pages: 103
Institution: Università degli Studi di Napoli Federico II
Department: Biologia strutturale e funzionale
PHD name: Genetica e medicina molecolare
PHD cycle: 21
PHD Coordinator:
nameemail
Bruni, Carmelo Brunobrucar@unina.it
Tutor:
nameemail
Lania, Luigiluigi.lania@unina.it
Date: 3 December 2008
Number of Pages: 103
Uncontrolled Keywords: Myc,ARF,P-TEFb and Tat
MIUR S.S.D.: Area 05 - Scienze biologiche > BIO/18 - Genetica
Date Deposited: 10 Nov 2009 10:50
Last Modified: 02 Dec 2014 11:45
URI: http://www.fedoa.unina.it/id/eprint/3183

Abstract

The aim of this thesis has been focused to analyze the positive regulation of Myc-mediated transcription by P-TEFb elongation complex, and the negative control exerted by p14ARF onco-suppressor on Myc's transactivation functions. Moreover in a parallel line of research I investigated the p14ARF involvement on Tat-mediated transcriptional transactivation of HIV-1 (Human Immunodeficiency Virus 1)gene.

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