Gargano, Barbara (2008) Positive and negative regulation of Myc-mediated transcription. [Tesi di dottorato] (Unpublished)
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|Item Type:||Tesi di dottorato|
|Uncontrolled Keywords:||Myc,ARF,P-TEFb and Tat|
|Date Deposited:||10 Nov 2009 10:50|
|Last Modified:||30 Apr 2014 19:35|
The aim of this thesis has been focused to analyze the positive regulation of Myc-mediated transcription by P-TEFb elongation complex, and the negative control exerted by p14ARF onco-suppressor on Myc's transactivation functions. Moreover in a parallel line of research I investigated the p14ARF involvement on Tat-mediated transcriptional transactivation of HIV-1 (Human Immunodeficiency Virus 1)gene.
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