Gargano, Barbara
(2008)
Positive and negative regulation of Myc-mediated transcription.
[Tesi di dottorato]
(Unpublished)
| Item Type: |
Tesi di dottorato
|
| Lingua: |
English |
| Title: |
Positive and negative regulation of Myc-mediated transcription |
| Creators: |
| Creators | Email |
|---|
| Gargano, Barbara | barbara.gargano@unina.it |
|
| Date: |
3 December 2008 |
| Number of Pages: |
103 |
| Institution: |
Università degli Studi di Napoli Federico II |
| Department: |
Biologia strutturale e funzionale |
| Dottorato: |
Genetica e medicina molecolare |
| Ciclo di dottorato: |
21 |
| Coordinatore del Corso di dottorato: |
| nome | email |
|---|
| Bruni, Carmelo Bruno | brucar@unina.it |
|
| Tutor: |
| nome | email |
|---|
| Lania, Luigi | luigi.lania@unina.it |
|
| Date: |
3 December 2008 |
| Number of Pages: |
103 |
| Uncontrolled Keywords: |
Myc,ARF,P-TEFb and Tat |
| Settori scientifico-disciplinari del MIUR: |
Area 05 - Scienze biologiche > BIO/18 - Genetica |
[error in script]
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| Date Deposited: |
10 Nov 2009 10:50 |
| Last Modified: |
02 Dec 2014 11:45 |
| URI: |
http://www.fedoa.unina.it/id/eprint/3183 |
| DOI: |
10.6092/UNINA/FEDOA/3183 |
Abstract
The aim of this thesis has been focused to analyze the positive regulation of Myc-mediated transcription by P-TEFb elongation complex, and the negative control exerted by p14ARF onco-suppressor on Myc's transactivation functions.
Moreover in a parallel line of research I investigated the p14ARF involvement on Tat-mediated transcriptional transactivation of HIV-1 (Human Immunodeficiency Virus 1)gene.
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