Cantile, Tiziana (2009) A BIOLOGICAL WAY IN CARIES PREVENTION. [Tesi di dottorato] (Inedito)

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Tipologia del documento: Tesi di dottorato
Lingua: English
Titolo: A BIOLOGICAL WAY IN CARIES PREVENTION
Autori:
AutoreEmail
Cantile, Tizianatizianacantile@yahoo.it
Data: 28 Novembre 2009
Numero di pagine: 97
Istituzione: Università degli Studi di Napoli Federico II
Dipartimento: Scienze odontostomatologiche e maxillo-facciali
Scuola di dottorato: Medicina clinica e sperimentale
Dottorato: Scienze odontostomatologiche
Ciclo di dottorato: 22
Coordinatore del Corso di dottorato:
nomeemail
Rengo, Sandro[non definito]
Tutor:
nomeemail
Ingenito, Aniello[non definito]
Data: 28 Novembre 2009
Numero di pagine: 97
Parole chiave: dental caries, remineralisation,casein phosphopeptides
Settori scientifico-disciplinari del MIUR: Area 06 - Scienze mediche > MED/28 - Malattie odontostomatologiche
Depositato il: 01 Dic 2009 12:29
Ultima modifica: 22 Gen 2015 11:51
URI: http://www.fedoa.unina.it/id/eprint/4136
DOI: 10.6092/UNINA/FEDOA/4136

Abstract

The intent of this research program was to determine a new way in caries prevention. The score was the valuation of anti-caries effects of bio-active molecules of natural origin (derived from animals), in order to elaborate a new preventive methodology. The under discussion molecules were casein phosphopeptides (CPPs) of dairy origin. For this aim, this research project has been divided in 5 part. Part 1: in vitro evaluation of the effectiveness of synthetic CPPs in dental caries prevention; Part 2: in vitro evaluation of the effectiveness of natural CPPs in dental caries prevention; Part 3: in vivo evaluation of the effectiveness of synthetic and natural CPPs in dental caries prevention; Part 4: in vivo evaluation of the antibacterial power of commercial yogurt against oral cariogenic microflora; Part 5: in vitro effectiveness of TMR (transverse micro-radiography) in assessing dental enamel demineralisation and remineralisation. The final score will be the creation of a new preventive methodology against dental caries. In fact, on the basis of the results obtained from this research, the protection against tooth decay could be done in different ways. First of all, people could protect their self simply by eating food containing CPPs , then these active principles could be exploited by nutritional and pharmacological industries by adding these bio-molecules both in food and in commercial products used for oral hygiene (mouth-rinse, toothpaste).

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