Cirillo, Francesco (2011) PATHOPHYSIOLOGY, CLINICAL FEATURES, AND MANAGEMENT OF CHILDREN WITH CHRONIC LIVER DISEASES. [Tesi di dottorato]

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Tipologia del documento: Tesi di dottorato
Lingua: Italiano
Titolo: PATHOPHYSIOLOGY, CLINICAL FEATURES, AND MANAGEMENT OF CHILDREN WITH CHRONIC LIVER DISEASES
Autori:
AutoreEmail
Cirillo, Francesco[non definito]
Data: 30 Novembre 2011
Numero di pagine: 66
Istituzione: Università degli Studi di Napoli Federico II
Dipartimento: Pediatria
Scuola di dottorato: Medicina clinica e sperimentale
Dottorato: Riproduzione, sviluppo ed accrescimento dell'uomo
Ciclo di dottorato: 24
Coordinatore del Corso di dottorato:
nomeemail
Pignata, Claudio[non definito]
Tutor:
nomeemail
Iorio, Raffaele[non definito]
Data: 30 Novembre 2011
Numero di pagine: 66
Parole chiave: liver disease, children
Settori scientifico-disciplinari del MIUR: Area 06 - Scienze mediche > MED/38 - Pediatria generale e specialistica
Depositato il: 25 Lug 2012 08:41
Ultima modifica: 17 Giu 2014 06:04
URI: http://www.fedoa.unina.it/id/eprint/9028

Abstract

our research starts from the assumption that only knowledge of unexplored aspects can be an important tool for advancing into the management of hepatic disorders in children. It should be a contribute to both provide a framework to understand pathophisiology of some hepatobiliary disorders and offer analyses of their clinical-laboratory manifestations and the strategies for managing them. This project might be also useful to create specific competences related to a integrated and multidisciplinary approach, as required in pediatric liver disease. Our study concerns four areas that still present several either pathogenetic or diagnostic uncertainties, focusing on the following aspects: 1. Role of cellular immunity in the pathogenesis of Biliary Atresia. 2. New clinical and therapeutic aspects in pediatric autoimmune liver disease. 3.Pediatric liver transplant: immunological features and complication of calcineurin inhibitors treatment. 4. Broadening the spectrum of UDCA indications

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