Spinelli, Vincenzo (2025) Bioinspired design toward the development of novel 3D additive manufactured scaffolds for bone tissue engineering and innovative technical solutions in experimental and clinical medicine. [Tesi di dottorato]
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| Tipologia del documento: | Tesi di dottorato |
|---|---|
| Lingua: | English |
| Titolo: | Bioinspired design toward the development of novel 3D additive manufactured scaffolds for bone tissue engineering and innovative technical solutions in experimental and clinical medicine |
| Autori: | Autore Email Spinelli, Vincenzo vincenzospinelli.job@gmail.com |
| Data: | 7 Febbraio 2025 |
| Numero di pagine: | 96 |
| Istituzione: | Università degli Studi di Napoli Federico II |
| Dipartimento: | Scienze Mediche Traslazionali |
| Dottorato: | Medicina clinica e sperimentale |
| Ciclo di dottorato: | 37 |
| Coordinatore del Corso di dottorato: | nome email Beguinot, Francesco beguino@unina.it |
| Tutor: | nome email Rengo, Sandro [non definito] Gloria, Antonio [non definito] Gallicchio, Vito [non definito] |
| Data: | 7 Febbraio 2025 |
| Numero di pagine: | 96 |
| Parole chiave: | bioinspired design for additive manufacturing; design of 3D scaffolds and innovative technical solutions; mechanical measurements |
| Settori scientifico-disciplinari del MIUR: | Area 09 - Ingegneria industriale e dell'informazione > ING-IND/12 - Misure meccaniche e termiche Area 09 - Ingegneria industriale e dell'informazione > ING-IND/15 - Disegno e metodi dell'ingegneria industriale Area 09 - Ingegneria industriale e dell'informazione > ING-IND/22 - Scienza e tecnologia dei materiali Area 09 - Ingegneria industriale e dell'informazione > ING-IND/34 - Bioingegneria industriale Area 06 - Scienze mediche > MED/28 - Malattie odontostomatologiche |
| Informazioni aggiuntive: | Dottorato di ricerca in Medicina Clinica e Sperimentale - 37° ciclo |
| Depositato il: | 17 Ott 2025 14:44 |
| Ultima modifica: | 09 Ago 2026 06:04 |
| URI: | https://www.fedoa.unina.it/id/eprint/16650 |
Abstract
In the current PhD thesis, several topics related to the engineering of biomedical devices were suitably analysed. First, some efforts were devoted to the bioinspired design of novel 3D additive manufactured scaffolds with improved and tailored morphological, mechanical, biological and functional features for bone tissue engineering. Interesting findings were found as a result of a suitable material-design combination, also involving the Voronoi design. In the second part of the thesis, the attention was focused on the analysis of highly reinforced acrylic resins for hard tissue engineering and their suitability to be additively manufactured through nozzle-based photo-printing, providing several interesting features and technical suggestions on the combined use of different kinds of composite materials and advanced technologies. Finally, the influence of the direct composite restoration on the fracture strength and failure modes of endodontically treated premolars restored with posts was critically analysed, showing the importance of the technical features and the adopted procedures towards a potential re-design of innovative devices and experimental setup.
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