KAUR, Jasneet (2025) 2D Nanomaterials in Biological Systems: Mechanisms of interaction and potential applications. [Tesi di dottorato]
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| Tipologia del documento: | Tesi di dottorato |
|---|---|
| Lingua: | English |
| Titolo: | 2D Nanomaterials in Biological Systems: Mechanisms of interaction and potential applications |
| Autori: | Autore Email KAUR, Jasneet Jasneet.kaur2@gmail.com |
| Data: | 29 Gennaio 2025 |
| Numero di pagine: | 175 |
| Istituzione: | Università degli Studi di Napoli Federico II |
| Dottorato: | Fisica |
| Ciclo di dottorato: | 36 |
| Coordinatore del Corso di dottorato: | nome email Canale, Vincenzo vincenzo.canale@unina.it |
| Tutor: | nome email Altucci, Carlo [non definito] |
| Data: | 29 Gennaio 2025 |
| Numero di pagine: | 175 |
| Parole chiave: | Two Dimensional nanomaterials (2DMs), Liquid phase exfoliation(LPE), Biocompatible, Degradation study. |
| Settori scientifico-disciplinari del MIUR: | Area 02 - Scienze fisiche > FIS/06 - Fisica per il sistema terra e il mezzo circumterrestre |
| Depositato il: | 18 Ott 2025 15:33 |
| Ultima modifica: | 12 Ago 2026 05:38 |
| URI: | https://www.fedoa.unina.it/id/eprint/16930 |
Abstract
This thesis explores the synthesis and characterization of two-dimensional (2D) nanomaterials, specifically antimonene nanosheets, using liquid phase exfoliation (LPE) in water, both with and without stabilizers. The nanosheets were analyzed using UV spectroscopy, Raman, FTIR spectroscopies, and DLS and TEM microscopy. In vitro biodegradation studies were conducted using horseradish peroxidase (HRP) and human myeloperoxidase (HMPO), confirming degradation through spectroscopic and microscopic techniques. Cell viability tests on the RAW 264.7 cell line assessed cytotoxicity, providing insights into the biocompatibility and safety profile of the degraded nanomaterials. Additionally, the study examined interactions between molybdenum disulfide (MoS2) nanosheets and biological molecules, highlighting the unique physical and mechanical interactions of 2D materials. This research aims to enhance our understanding of the biological and environmental fates of engineered 2D nanosheets, advancing their application in the biomedical field.
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