Sacco, Oriana (2025) Identification, characterisation and exploitation of (hyper)thermophilic carbohydrate active enzymes for biocatalysis and biotransformation processes. [Tesi di dottorato]
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| Tipologia del documento: | Tesi di dottorato |
|---|---|
| Lingua: | English |
| Titolo: | Identification, characterisation and exploitation of (hyper)thermophilic carbohydrate active enzymes for biocatalysis and biotransformation processes |
| Autori: | Autore Email Sacco, Oriana oriana.sacco@unina.it |
| Data: | 9 Dicembre 2025 |
| Numero di pagine: | 168 |
| Istituzione: | Università degli Studi di Napoli Federico II |
| Dottorato: | Biotecnologie |
| Ciclo di dottorato: | 38 |
| Coordinatore del Corso di dottorato: | nome email Moracci, Marco marco.moracci@unina.it |
| Tutor: | nome email Moracci, Marco [non definito] Cobucci-Ponzano, Beatrice [non definito] |
| Data: | 9 Dicembre 2025 |
| Numero di pagine: | 168 |
| Parole chiave: | Hyperthermophiles; Carbohydrate active eymes; Bioprocesses |
| Settori scientifico-disciplinari del MIUR: | Area 05 - Scienze biologiche > BIO/10 - Biochimica |
| Informazioni aggiuntive: | Dottorato 38esimo ciclo |
| Depositato il: | 21 Dic 2025 11:16 |
| Ultima modifica: | 12 Ago 2026 05:38 |
| URI: | https://www.fedoa.unina.it/id/eprint/17027 |
Abstract
This PhD thesis investigated novel (hyper)thermophilic carbohydrate-active enzymes (CAZymes) with the aim of enabling more efficient and sustainable biocatalytic and biotransformation processes. The work combined fundamental and applied approaches: metagenomic discovery and biochemical characterisation of enzymes with unique properties, and the application of CAZymes to valorise agro-industrial residues, such as spent coffee grounds and olive-oil by-products, and to modify starch granules to obtain added-value bioproducts. In parallel, the thesis examined how institutional frameworks support industrial biotechnology, aligning the RIS3 Campania strategy with the vision of the European research Infrastructure on Biotechnology IBISBA. This contributed to mapping regional innovation needs and integrating research-infrastructure services into regional development strategies, particularly for start-ups and SMEs. Overall, the thesis represented a multidisciplinary effort linking biochemistry, biotechnology, and innovation policy to advance sustainable biotechnological solutions with real-world impact.
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