Gallo, Carmela (2015) Sterols mediate deadly messages in marine diatoms. [Tesi di dottorato]

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Item Type: Tesi di dottorato
Lingua: English
Title: Sterols mediate deadly messages in marine diatoms
Creators:
CreatorsEmail
Gallo, Carmelacarmenpic@hotmail.it
Date: 31 March 2015
Number of Pages: 158
Institution: Università degli Studi di Napoli Federico II
Department: Biologia
Scuola di dottorato: Scienze biologiche
Dottorato: Biologia applicata
Ciclo di dottorato: 27
Coordinatore del Corso di dottorato:
nomeemail
Ricca, Ezioezio.ricca@unina.it
Tutor:
nomeemail
Fontana, AngeloUNSPECIFIED
d'Ippolito, GiulianaUNSPECIFIED
Date: 31 March 2015
Number of Pages: 158
Uncontrolled Keywords: diatom-sterol-Programmed Cell Death
Settori scientifico-disciplinari del MIUR: Area 05 - Scienze biologiche > BIO/10 - Biochimica
Aree tematiche (7° programma Quadro): BIOTECNOLOGIE, PRODOTTI ALIMENTARI E AGRICOLTURA > Scienze della vita, biotecnologia e biochimica per prodotti e processi non-alimentari sostenibili
Date Deposited: 07 Apr 2015 08:22
Last Modified: 14 May 2016 01:00
URI: http://www.fedoa.unina.it/id/eprint/10349
DOI: 10.6092/UNINA/FEDOA/10349

Abstract

The marine diatoms are unicellular algae that play an important ecological role in the global primary production These unicellular protists are able to survive and proliferate in a wide range of environmental conditions, by adapting their metabolism through mechanisms largely unknown. Understanding these processes is of great ecological interest and can have wide application in different biotechnological sectors.This thesis has identified for the first time the role of secondary metabolites with pro apoptotic effects in diatoms. In addition to the different tools that have been developed to carry out this study, the major outcome of this work concerns the first establishment of a cellular mechanism to control Programmed Cell Death in the lineage and the first direct elucidation of the biosynthesis in these organisms.

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