Di Palo, Giacomo (2016) The Intertwined Roles of DNA Damage and Transcription. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato |
|---|---|
| Resource language: | English |
| Title: | The Intertwined Roles of DNA Damage and Transcription |
| Creators: | Creators Email Di Palo, Giacomo giacomo.dipalo@unina.it |
| Date: | 30 March 2016 |
| Number of Pages: | 69 |
| Institution: | Università degli Studi di Napoli Federico II |
| Department: | Medicina Molecolare e Biotecnologie Mediche |
| Scuola di dottorato: | Medicina molecolare |
| Dottorato: | Genetica e medicina molecolare |
| Ciclo di dottorato: | 28 |
| Coordinatore del Corso di dottorato: | nome email Nitsch, Lucio lucio.nitsch@unina.it |
| Tutor: | nome email Lania, Luigi UNSPECIFIED |
| Date: | 30 March 2016 |
| Number of Pages: | 69 |
| Keywords: | DNA damage, transcription, OxiDIP-Seq, 8oxodG, double-strand brea |
| Settori scientifico-disciplinari del MIUR: | Area 05 - Scienze biologiche > BIO/11 - Biologia molecolare Area 05 - Scienze biologiche > BIO/18 - Genetica Area 01 - Scienze matematiche e informatiche > INF/01 - Informatica |
| Date Deposited: | 13 Apr 2016 11:59 |
| Last Modified: | 31 Oct 2016 09:53 |
| URI: | http://www.fedoa.unina.it/id/eprint/10833 |
Collection description
DNA damage and transcription are two interconnected events. Transcription can induce damage and scheduled DNA damage can be required for transcription. Here, we analyzed genome-wide distribution of 8oxodG-marked oxidative DNA damage obtained by OxiDIP-Seq, and we found a correlation with transcription of protein coding genes.
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