Maglione, Marco (2017) Towards a global assessment of pediatric non-cystic fibrosis chronic pulmonary disorders: new insights in disease diagnosis and monitoring. [Tesi di dottorato]

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Tipologia del documento: Tesi di dottorato
Lingua: English
Titolo: Towards a global assessment of pediatric non-cystic fibrosis chronic pulmonary disorders: new insights in disease diagnosis and monitoring
Autori:
AutoreEmail
Maglione, Marcomarcomaglione84@gmail.com
Data: 30 Marzo 2017
Numero di pagine: 86
Istituzione: Università degli Studi di Napoli Federico II
Dipartimento: Scienze Mediche Traslazionali
Scuola di dottorato: Medicina clinica e sperimentale
Dottorato: Medicina clinica e sperimentale
Ciclo di dottorato: 29
Coordinatore del Corso di dottorato:
nomeemail
Marone, Gianni[non definito]
Tutor:
nomeemail
Santamaria, Francesca[non definito]
Data: 30 Marzo 2017
Numero di pagine: 86
Parole chiave: non-cystic fibrosis chronic pulmonary disorders; children
Settori scientifico-disciplinari del MIUR: Area 06 - Scienze mediche > MED/38 - Pediatria generale e specialistica
Depositato il: 28 Apr 2017 12:16
Ultima modifica: 13 Mar 2018 10:35
URI: http://www.fedoa.unina.it/id/eprint/11470
DOI: 10.6093/UNINA/FEDOA/11470

Abstract

Classification of chronic lung disease (CLD) in children has traditionally distinguished cystic fibrosis (CF), the most common lethal inherited genetic disorder worldwide, from less common non-CF disorders, a heterogeneous group of conditions with different etiologies, but overlapping clinical features. While in CF the multi-organ involvement has traditionally required a systemic approach to patients’ care, not limited to respiratory issues, in non-CF CLD this aspect has often been neglected. However, an increasing awareness is emerging regarding the need to adequately address issues such as growth, nutrition and psychological aspects, sometimes underestimated by pediatric respiratory physicians. In particular, nutritional status and growth in pediatric non-CF CLD are strongly related to lung impairment and these two elements may deeply influence each other. Furthermore, in non-CF CLD poor attention has been dedicated to the impact of the disease on patients’ life, whereas quality of life represents a crucial parameter to assess disease severity, efficacy of treatments and to highlight areas of possible improvement in patients’ care. Given these premises the present phD thesis aimed at (1) evaluating currently used and emerging tools in the diagnosis and monitoring of pediatric non-CF CLD and at (2) assessing the role of nutritional status assessment in the management of non-CF CLD children

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