Perrino, Giansimone (2017) Modeling and control of gene expression dynamics in yeast. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato | ||||||
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| Lingua: | English | ||||||
| Title: | Modeling and control of gene expression dynamics in yeast | ||||||
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| Date: | 7 April 2017 | ||||||
| Number of Pages: | 121 | ||||||
| Institution: | Università degli Studi di Napoli Federico II | ||||||
| Department: | Ingegneria Elettrica e delle Tecnologie dell'Informazione | ||||||
| Dottorato: | Information technology and electrical engineering | ||||||
| Ciclo di dottorato: | 29 | ||||||
| Coordinatore del Corso di dottorato: |
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| Date: | 7 April 2017 | ||||||
| Number of Pages: | 121 | ||||||
| Uncontrolled Keywords: | control theory; synthetic biology; gene expression; mathematical modeling | ||||||
| Settori scientifico-disciplinari del MIUR: | Area 09 - Ingegneria industriale e dell'informazione > ING-IND/34 - Bioingegneria industriale Area 09 - Ingegneria industriale e dell'informazione > ING-INF/04 - Automatica |
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| Date Deposited: | 09 May 2017 14:40 | ||||||
| Last Modified: | 08 Mar 2018 13:33 | ||||||
| URI: | http://www.fedoa.unina.it/id/eprint/11610 | ||||||
| DOI: | 10.6093/UNINA/FEDOA/11610 |
Abstract
Synthetic biology is a novel research field which aims to engineer new functionalities in living cells with the final goal of controlling cellular behavior for a number of uses, ranging from energy, to environment, to medicine. Here, I contributed to the emerging role of control theory in synthetic biology. Exploring the concept of negative feedback loop, I extended the field of controlling cellular processes by devising novel approaches to model and control gene expression dynamics in a population of living cells.
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