Telesco, Mariarosaria (2021) Lab on chip for cell separation. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato |
|---|---|
| Resource language: | English |
| Title: | Lab on chip for cell separation |
| Creators: | Creators Email Telesco, Mariarosaria mariarosariatelesco@live.it |
| Date: | 15 July 2021 |
| Number of Pages: | 125 |
| Institution: | Università degli Studi di Napoli Federico II |
| Department: | Ingegneria Chimica, dei Materiali e della Produzione Industriale |
| Dottorato: | Ingegneria dei prodotti e dei processi industriali |
| Ciclo di dottorato: | 33 |
| Coordinatore del Corso di dottorato: | nome email D'Anna, Andrea anddanna@unina.it |
| Tutor: | nome email Causa, Filippo UNSPECIFIED Netti, Paolo Antonio UNSPECIFIED |
| Date: | 15 July 2021 |
| Number of Pages: | 125 |
| Keywords: | lab on chip, cell separation, viscoelastic flow |
| Settori scientifico-disciplinari del MIUR: | Area 09 - Ingegneria industriale e dell'informazione > ING-IND/34 - Bioingegneria industriale |
| Date Deposited: | 20 Jul 2021 12:03 |
| Last Modified: | 07 Jun 2023 11:21 |
| URI: | http://www.fedoa.unina.it/id/eprint/13594 |
Collection description
Cells are the basic functional units of human life, which led researcher in molecular biology, biochemistry, and biotechnology focus their skills to obtain efficient and cost-effective methods for cell enrichment, isolation, and handling. For instance, the main problem of biochemical, pharmaceutical, and clinical studies is the requirement of homogenous cell populations, which consist of a single cell type. For these reasons, the aim of this work is to develop a microfluidic platform to study the influence of fluid, particle, and cell properties on the separation efficiency. To obtain that, we have designed, fabricated, and tested a novel microfluidic device, that exploit the effect of viscoelastic fluid properties on biophysical cell properties to separate different cell types in-flow.
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