Chiurazzi, Martina (2021) The effects of a hypocaloric diet and cinchona supplementation on nutritional status and body composition in a population of obese adults. [Tesi di dottorato]

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Item Type: Tesi di dottorato
Resource language: English
Title: The effects of a hypocaloric diet and cinchona supplementation on nutritional status and body composition in a population of obese adults
Creators:
Creators
Email
Chiurazzi, Martina
martina.chiurazzi88@gmail.com
Date: 11 February 2021
Number of Pages: 47
Institution: Università degli Studi di Napoli Federico II
Department: Medicina Clinica e Chirurgia
Dottorato: Terapie avanzate biomediche e chirurgiche
Ciclo di dottorato: 33
Coordinatore del Corso di dottorato:
nome
email
Di Minno, Giovanni
di minno@unina.it
Tutor:
nome
email
Di Minno, Matteo Nicola Dario
UNSPECIFIED
Date: 11 February 2021
Number of Pages: 47
Keywords: Cardiovascular disease, obesity, cinchona, body composition, diet.
Settori scientifico-disciplinari del MIUR: Area 05 - Scienze biologiche > BIO/09 - Fisiologia
Area 06 - Scienze mediche > MED/09 - Medicina interna
Date Deposited: 24 Feb 2021 09:46
Last Modified: 07 Jun 2023 10:28
URI: http://www.fedoa.unina.it/id/eprint/13978

Collection description

Cardiovascular disease (CVD) is the leading cause of mortality and disability in humans worldwide. Obesity is a chronic disease present worldwide, considered as an etiological risk factors that can cause the onset of cardiovascular diseases. Currently, the most effective therapies to reduce the cardiovascular risk associated with obesity is an healthy lifestyle represented by dietary changes and physical activity. The aim of this study was to evaluate the effects of a hypocaloric diet associated with a cinchona supplementation on nutritional status and body composition in a population of obese adults. A total of forty obese subjects of both sexes with Body Mass Index (BMI) ≥ 30 kg/m2 attending at Outpatients Clinic of the Departmental program "Physiology Nutrition Unit ", School of Medicine, "Federico II" University of Naples, were recruited. Subjects were randomized into 2 groups. The first group was treated with hypocaloric diet for 2 months plus supplementation of Cinchona (C group); the second one was treated with hypocaloric diet for 2 months plus a placebo supplementation (P group). Anthropometric measurements as well as bioimpedance analysis, abdominal fat distribution and basal metabolic rate were evaluated at baseline and after 60 days. At the end of observations, we observed a significant improvement in nutritional status and body composition in patients belonging to C group compared with subjects belonging to P group. . Therefore, this study demonstrates that the association of hypocaloric diet with a nutraceutical supplementation is able to induce a more significant weight loss than that obtained with a hypocaloric diet alone.

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