PAOLILLO, ROBERTA (2021) New translational strategies for heart failure treatment. [Tesi di dottorato]
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| Tipologia del documento: | Tesi di dottorato |
|---|---|
| Lingua: | English |
| Titolo: | New translational strategies for heart failure treatment |
| Autori: | Autore Email PAOLILLO, ROBERTA ROBE.PAOLILLO@GMAIL.COM |
| Data: | 29 Dicembre 2021 |
| Numero di pagine: | 53 |
| Istituzione: | Università degli Studi di Napoli Federico II |
| Dipartimento: | Scienze Biomediche Avanzate |
| Dottorato: | Cardiovascular Pathophysiology and Therapeutics |
| Ciclo di dottorato: | 34 |
| Coordinatore del Corso di dottorato: | nome email IZZO, RAFFAELE rafizzo@unina.it |
| Tutor: | nome email PERRINO, CINZIA [non definito] |
| Data: | 29 Dicembre 2021 |
| Numero di pagine: | 53 |
| Parole chiave: | HEART FAILURE, METABOLISM, BIOMARKER, GUT MICROBIOTA |
| Settori scientifico-disciplinari del MIUR: | Area 06 - Scienze mediche > MED/11 - Malattie dell'apparato cardiovascolare |
| Depositato il: | 29 Dic 2021 15:17 |
| Ultima modifica: | 28 Feb 2024 12:05 |
| URI: | http://www.fedoa.unina.it/id/eprint/14268 |
Abstract
Despite important advances in diagnosis and treatment, heart failure (HF) remains a relentless syndrome with substantial morbidity and dismal prognosis. Although implementation and optimization of existing technologies and drugs may lead to better management of HF, new or alternative strategies are desirable. In this regard, basic science is expected to give fundamental inputs to accomplish these goals, by collecting evidence that may lay the foundations for or allow a better understanding of novel diagnostic, prognostic or therapeutic tools1. Here, we discuss our recent basic science insights with potential clinical impact on HF. In the effort of providing a comprehensive overview, the main domains of translational research in HF are covered: cardiac metabolism, gut microbiota and systemic inflammation and therapeutic strategies
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