Lembo, Maria (2021) Advanced novel imaging tools for detection of early morphological and functional impairment in cardiovascular diseases. [Tesi di dottorato]
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Tipologia del documento: | Tesi di dottorato |
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Lingua: | English |
Titolo: | Advanced novel imaging tools for detection of early morphological and functional impairment in cardiovascular diseases |
Autori: | Autore Email Lembo, Maria mari.lembo@gmail.com |
Data: | Dicembre 2021 |
Numero di pagine: | 119 |
Istituzione: | Università degli Studi di Napoli Federico II |
Dipartimento: | Scienze Biomediche Avanzate |
Dottorato: | Cardiovascular Pathophysiology and Therapeutics |
Ciclo di dottorato: | 34 |
Coordinatore del Corso di dottorato: | nome email Barbato, Emanuele emanuele.barbato@unina.it |
Tutor: | nome email Raffaele, Izzo [non definito] |
Data: | Dicembre 2021 |
Numero di pagine: | 119 |
Parole chiave: | Advanced imaging tools |
Settori scientifico-disciplinari del MIUR: | Area 06 - Scienze mediche > MED/11 - Malattie dell'apparato cardiovascolare Area 06 - Scienze mediche > MED/50 - Scienze tecniche mediche applicate |
Depositato il: | 29 Dic 2021 08:15 |
Ultima modifica: | 28 Feb 2024 11:33 |
URI: | http://www.fedoa.unina.it/id/eprint/14338 |
Abstract
Advanced imaging tools provide detailed information about the structure and function of the heart and the cardiovascular system, essential in both the diagnostic process and patients’ management. Early diagnosis of cardiac modifications and arterial disease together with the identification of subclinical organ damage has become crucial for a timely and adequate treatment, aiming at not only the avoidance of irreparable organ damage but also trying to confine injury progression 1. Beyond standard echo-Doppler echocardiography, which remains among the most simple but accurate methods for the investigation of cardiac and vascular remodelling and systolic and diastolic dysfunction, advanced imaging techniques are emerging for their sensitive capability of recognizing early myocardial and vascular impairment in many cardiovascular diseases 1, 2. Those imaging methods, including speckle tracking and three-dimensional (3D) echocardiography, cardiac magnetic resonance imaging (MRI), computed tomography (CT) and Positron emission tomography-computed tomography (PET-CT), can help, in different ways, in the detection of subclinical disease and/or in the identification of cardiovascular changes. Those techniques are able to ameliorate diagnostic accuracy and provide markers to further improve risk prediction and optimize patient care. In addition, imaging tools are easily appliable into both clinical and research practice thanks to novel approaches and software advancements which sensibly reduce the time for analyses.
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