Cascone, Francesco Davide (2022) Additive Manufacturing and Design Strategies for the Development of Advanced Biomedical Devices. [Tesi di dottorato]

	Text CASCONE_COMPLETA_34.pdf Visibile a [TBR] Repository staff only Download (20MB) | Request a copy
Preview	Text Cascone_PARZIALE_34.pdf Download (4MB) | Preview

Collection description

The study covers design methodologies for Additive Manufacturing (AM) applied to biomedical devices. In particular, the application of Triply Periodical Minimal Surfaces to implants plays a role in minimizing issues related to phenomena occurring at the bone-device interface. The capabilities of AM technologies have their foundation on enhancing shape, functional and material complexity leading to innovative applications. Many methodologies of DfAM are implemented at the state of the art and they include Light-weighting, Texturing and process Simulation. The light-weighting approaches are mostly represented by Topology Optimization and Lattice Structures. AM covers a wide range of materials ranging from polymers to metal and composites. The main technology for metal AM and biomedical devices is Selective Laser Melting (SLM). The AM process enables the customization of components resulting in patientspecific devices. Many applications have been carried out from cranioplasty to orthopedic implant. The material commonly used is Ti6Al4V which properties are appreciated in many fields and they are biocompatibility and corrosion resistance for biomedical applications. 4 The structure of the thesis is divided into four chapters. The first provides a general overview of the state of the art of Additive Manufacturing with focus on biomedical applications and methodologies applied to the next chapters. In Chapter II the investigation of a class of lattice structures, TPMS with variable thickness, is analyzed and mechanical properties coming from simulation are obtained. The work is completed by a case study of application of these structures on femoral hip stem. The third chapter presents the parametric design for customized Intervertebral Body Fusion Device manufactured in Metal AM with analyses and validation of the prototypes and the generation of a family of devices consisting in thirty-two configurations. Also, preliminary biological tests are performed to validate the full model. The last chapter presents the study of an interface for users with speech disorder and motor impairments.

Downloads

Actions (login required)

View Item