Autiero, Maddalena and Laccetti, Paolo and Marotta, Marcello and Quarto, Maria and Riccio, Patrizia and Roberti, Giuseppe (2009) Hematoporphyrin-mediated fluorescence reflectance imaging: application to early tumor detection in vivo in small animals. [Pubblicazione in rivista scientifica]Full text not available from this repository.
|Item Type:||Pubblicazione in rivista scientifica|
|Uncontrolled Keywords:||Hematoporphyrins, Tumor, Fluorescence, Lasers, Early diagnosis|
|Date Deposited:||21 Oct 2010 06:57|
|Last Modified:||30 Apr 2014 19:43|
The in vivo early detection of subcutaneous human tumors implanted in small animals was studied by laser-induced fluorescence reflectance imaging (FRI), with a hematoporphyrin (HP) compound as an exogenous optical contrast agent. Tumor detection was shown to be possible just 3 days after the inoculation of tumor cells, when tumors were neither visible nor palpable. However, this detection capability is limited to a temporal window of approximately 100 h from HP administration and to a low optical contrast of the tumor (<2).
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