Amato, Ivana (2010) ANTI-MICROBIAL EFFECTS OF PHENOLIC EXTRACTS ON CARIOGENIC ORAL BACTERIA: EXPERIMENTAL STUDY. [Tesi di dottorato] (Inedito)

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Tipologia del documento: Tesi di dottorato
Lingua: English
Titolo: ANTI-MICROBIAL EFFECTS OF PHENOLIC EXTRACTS ON CARIOGENIC ORAL BACTERIA: EXPERIMENTAL STUDY
Autori:
AutoreEmail
Amato, Ivanaivana.amato@libero.it
Data: 29 Novembre 2010
Numero di pagine: 78
Istituzione: Università degli Studi di Napoli Federico II
Dipartimento: Scienze odontostomatologiche e maxillo-facciali
Scuola di dottorato: Medicina clinica e sperimentale
Dottorato: Scienze odontostomatologiche
Ciclo di dottorato: 23
Coordinatore del Corso di dottorato:
nomeemail
Rengo, Sandrosanrengo@unina.it
Tutor:
nomeemail
Ingenito, Anielloingenito@unina.it
Data: 29 Novembre 2010
Numero di pagine: 78
Parole chiave: polyphenols, caries prevention, anti-bacterial effect.
Settori scientifico-disciplinari del MIUR: Area 06 - Scienze mediche > MED/28 - Malattie odontostomatologiche
Depositato il: 05 Dic 2010 10:31
Ultima modifica: 30 Apr 2014 19:44
URI: http://www.fedoa.unina.it/id/eprint/8078
DOI: 10.6092/UNINA/FEDOA/8078

Abstract

The intent of this research program was to evaluate the anti-caries effects of bio-active molecules of natural origin (derived from plants), in order to elaborate a new preventive methodology. The under discussion molecules were polyphenols. For this aim, this research project has been divided in 5 part. Part 1: In vitro evaluation of the anti-microbial effects of phenolic extracts on cariogenic oral bacteria; Part 2: Evaluation of citotoxicity effect and antimicrobial properties of Camelia sinensis extract against cariogenic microflora; Part 3: Evaluation of citotoxicity effect and antibacterial power of Plantago lanceolata extract against oral cariogenic microflora. The results obtained from this research show the anticariogenic activity of polyphenols both in vitro and in vivo experiments. They could open a promising avenue of applications because these compounds largely occur in flowering plants and could be used at a reasonable cost in the preparation of specific remedies. In fact, these active principles could be exploited by nutritional and pharmacological industries by adding these bio-molecules both in food and in commercial products used for oral hygiene (mouth-rinse, toothpaste) in order to create a new preventive methodology against dental caries.

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