Santangelo, Fabrizia (2021) SAFETY AND ACCEPTABILITY OF INTRAUTERINE DEVICE IN WOMEN WITH EPILEPSY. [Tesi di dottorato]
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| Tipologia del documento: | Tesi di dottorato |
|---|---|
| Lingua: | English |
| Titolo: | SAFETY AND ACCEPTABILITY OF INTRAUTERINE DEVICE IN WOMEN WITH EPILEPSY |
| Autori: | Autore Email Santangelo, Fabrizia fabriziasantangelo@hotmail.it |
| Data: | 18 Novembre 2021 |
| Numero di pagine: | 41 |
| Istituzione: | Università degli Studi di Napoli Federico II |
| Dipartimento: | Neuroscienze e Scienze Riproduttive ed Odontostomatologiche |
| Dottorato: | Neuroscienze |
| Ciclo di dottorato: | 34 |
| Coordinatore del Corso di dottorato: | nome email taglialatela, maurizio maurizio.taglialatela@unina.it |
| Tutor: | nome email Bifulco, Giuseppe [non definito] |
| Data: | 18 Novembre 2021 |
| Numero di pagine: | 41 |
| Parole chiave: | epilepsy, contraception, intrauterine device, antiepileptic drugs |
| Settori scientifico-disciplinari del MIUR: | Area 06 - Scienze mediche > MED/26 - Neurologia Area 06 - Scienze mediche > MED/40 - Ginecologia e ostetricia |
| Depositato il: | 17 Dic 2021 08:24 |
| Ultima modifica: | 28 Feb 2024 11:34 |
| URI: | http://www.fedoa.unina.it/id/eprint/14341 |
Abstract
Epilepsy is one of the most frequent chronic neurological disorders that affects an estimated 25 million women worldwide. Contraception is an essential health concern for women with epilepsy (WWE) because most of antiepileptic drugs (AEDs) are potentially teratogenic. Oral contraceptives (OCs) are commonly prescribed for young women, however bidirectional interactions between some AEDs and OCs may compromise contraceptive efficacy, seizure control, or both. The main objective of this study is to characterize the safety of two different intrauterine device (copper or progestin) in WWE, by measuring AEDs concentrations and seizures before and after initiating the IUD in order to evaluate if the progestin IUD affects the serum levels of AEDs differently from the copper IUD.
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