Santangelo, Fabrizia (2021) SAFETY AND ACCEPTABILITY OF INTRAUTERINE DEVICE IN WOMEN WITH EPILEPSY. [Tesi di dottorato]

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Item Type:	Tesi di dottorato
Resource language:	English
Title:	SAFETY AND ACCEPTABILITY OF INTRAUTERINE DEVICE IN WOMEN WITH EPILEPSY
Creators:	Creators Email Santangelo, Fabrizia fabriziasantangelo@hotmail.it
Date:	18 November 2021
Number of Pages:	41
Institution:	Università degli Studi di Napoli Federico II
Department:	Neuroscienze e Scienze Riproduttive ed Odontostomatologiche
Dottorato:	Neuroscienze
Ciclo di dottorato:	34
Coordinatore del Corso di dottorato:	nome email taglialatela, maurizio maurizio.taglialatela@unina.it
Tutor:	nome email Bifulco, Giuseppe UNSPECIFIED
Date:	18 November 2021
Number of Pages:	41
Keywords:	epilepsy, contraception, intrauterine device, antiepileptic drugs
Settori scientifico-disciplinari del MIUR:	Area 06 - Scienze mediche > MED/26 - Neurologia Area 06 - Scienze mediche > MED/40 - Ginecologia e ostetricia
Date Deposited:	17 Dec 2021 08:24
Last Modified:	28 Feb 2024 11:34
URI:	http://www.fedoa.unina.it/id/eprint/14341

Collection description

Epilepsy is one of the most frequent chronic neurological disorders that affects an estimated 25 million women worldwide. Contraception is an essential health concern for women with epilepsy (WWE) because most of antiepileptic drugs (AEDs) are potentially teratogenic. Oral contraceptives (OCs) are commonly prescribed for young women, however bidirectional interactions between some AEDs and OCs may compromise contraceptive efficacy, seizure control, or both. The main objective of this study is to characterize the safety of two different intrauterine device (copper or progestin) in WWE, by measuring AEDs concentrations and seizures before and after initiating the IUD in order to evaluate if the progestin IUD affects the serum levels of AEDs differently from the copper IUD.

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