Casertano, Melania (2022) Selection of probiotic microorganisms with potential psychobiotic activity. [Tesi di dottorato]
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| Item Type: | Tesi di dottorato |
|---|---|
| Resource language: | English |
| Title: | Selection of probiotic microorganisms with potential psychobiotic activity |
| Creators: | Creators Email Casertano, Melania melania.casertano@unina.it |
| Date: | 9 March 2022 |
| Number of Pages: | 136 |
| Institution: | Università degli Studi di Napoli Federico II |
| Department: | Agraria |
| Dottorato: | Scienze agrarie e agroalimentari |
| Ciclo di dottorato: | 34 |
| Coordinatore del Corso di dottorato: | nome email Barone, Amalia ambarone@unina.it |
| Tutor: | nome email Ercolini, Danilo UNSPECIFIED Fogliano, Vincenzo UNSPECIFIED |
| Date: | 9 March 2022 |
| Number of Pages: | 136 |
| Keywords: | Psychobiotics, gut microbiota, mental health |
| Settori scientifico-disciplinari del MIUR: | Area 07 - Scienze agrarie e veterinarie > AGR/15 - Scienze e tecnologie alimentari |
| Date Deposited: | 18 Mar 2022 10:40 |
| Last Modified: | 28 Feb 2024 14:24 |
| URI: | http://www.fedoa.unina.it/id/eprint/14497 |
Collection description
Psychobiotics include a novel class of probiotic microorganisms that convey benefit upon the host's mental health via the dynamic microbiota-gut-brain crosstalk. However, the specific probiotic strains and the way how they exert their beneficial effect still need to be investigated and assessed as well as their effects in the alleviation of stress and their effect on several cognitive performance domains. In this study we performed pre-clinical and clinical studies to I) evaluate the ability of probiotic strains to produce neurotransmitters in substrates enriched in precursors, II) investigate the interaction between the gut microbiota and the selected psychobiotic strains, III) assess the translatability of the psychobiotic activity of neurotransmitters-producing probiotics in a clinical intervention on healthy humans.
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