Casertano, Melania (2022) Selection of probiotic microorganisms with potential psychobiotic activity. [Tesi di dottorato]


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Item Type: Tesi di dottorato
Resource language: English
Title: Selection of probiotic microorganisms with potential psychobiotic activity
Date: 9 March 2022
Number of Pages: 136
Institution: Università degli Studi di Napoli Federico II
Department: Agraria
Dottorato: Scienze agrarie e agroalimentari
Ciclo di dottorato: 34
Coordinatore del Corso di dottorato:
Ercolini, DaniloUNSPECIFIED
Fogliano, VincenzoUNSPECIFIED
Date: 9 March 2022
Number of Pages: 136
Keywords: Psychobiotics, gut microbiota, mental health
Settori scientifico-disciplinari del MIUR: Area 07 - Scienze agrarie e veterinarie > AGR/15 - Scienze e tecnologie alimentari
Date Deposited: 18 Mar 2022 10:40
Last Modified: 28 Feb 2024 14:24

Collection description

Psychobiotics include a novel class of probiotic microorganisms that convey benefit upon the host's mental health via the dynamic microbiota-gut-brain crosstalk. However, the specific probiotic strains and the way how they exert their beneficial effect still need to be investigated and assessed as well as their effects in the alleviation of stress and their effect on several cognitive performance domains. In this study we performed pre-clinical and clinical studies to I) evaluate the ability of probiotic strains to produce neurotransmitters in substrates enriched in precursors, II) investigate the interaction between the gut microbiota and the selected psychobiotic strains, III) assess the translatability of the psychobiotic activity of neurotransmitters-producing probiotics in a clinical intervention on healthy humans.


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