Fiengo, Marcella (2013) Gene expression pattern of relaxins and their receptors in Danio rerio. [Tesi di dottorato]

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Item Type:	Tesi di dottorato
Lingua:	English
Title:	Gene expression pattern of relaxins and their receptors in Danio rerio
Creators:	Creators Email Fiengo, Marcella marcella.fiengo@unina.it
Date:	29 March 2013
Number of Pages:	76
Institution:	Università degli Studi di Napoli Federico II
Department:	Scienze biologiche
Scuola di dottorato:	Scienze biologiche
Dottorato:	Biochimica e biologia cellulare e molecolare
Ciclo di dottorato:	25
Coordinatore del Corso di dottorato:	nome email Arcari, Paolo paolo.arcari@unina.it
Tutor:	nome email Aniello, Francesco faniello@unina.it
Date:	29 March 2013
Number of Pages:	76
Uncontrolled Keywords:	zebrafish; relaxin; development.
Settori scientifico-disciplinari del MIUR:	Area 05 - Scienze biologiche > BIO/11 - Biologia molecolare
Date Deposited:	10 Apr 2013 15:50
Last Modified:	17 Jun 2014 06:04
URI:	http://www.fedoa.unina.it/id/eprint/9206

Abstract

The relaxin (RLN) peptides exert different biological effects ranging from reproduction to regulating central nervous processes. Until now, few studies have been performed in embryonic development and in vertebrate models beyond mammals. I used zebrafish, as experimental model, to characterize the spatial and temporal expression pattern of the relaxin/receptor system in vertebrate embryogenesis.I showed that, in embryonic development, the different expression areas of relaxin/receptor system and probably their function are conserved between mammals and fishes. Overall, my data provided evidence that the relaxin/receptor system is active during zebrafish embryogenesis, and that their expression territories and probably their function are conserved between mammals and fishes.

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